Wistar Han®
RccHan®:WIST
HsdHan®:WIST
Albino. Derived at Biological Research Laboratories Limited (BRL), formerly RCC, now Harlan Laboratories Ltd., Fullinsdorf, Switzerland from original colony at Zentralinstitute fur Versuchstierzucht, Hannover in 1989. Transferred to Harlan Sprague-Dawley, Inc. in 1993. In 2004 Envigo acquired RCC Ltd. and new breeding stock was transferred in 2008 (nomenclature RccHanR:WIST). Unlike competitive models, the RccHanR:WIST rat has been maintained from the original nucleus of 156 breeding pairs in Hannover, Germany.
Han® is a registered trademark of Envigo.
Characteristics
- Litter average: 9,5
- Docile disposition
- Global breeding and monitoring system - consistent research outcomes
- Longer survival - reduced costs, improved study outcomes
- Lower spontaneous tumor incidence - reduced research variables, improved animal welfare
- Smaller body size - less compound and cost
Research use
- Hematology
- Clinical chemistry
Other available data
- Toxicology
- Teratology
- General purpose
- Oncology
- Aging
20 years of stable control data at envigo.com/toxicology
Acute to oncogenicity studies – 3, 6, 12 and 24 months
- Survival rates
- Growth
- Food and water consumption
- Clinical observations
- Functional observation battery
- Opthalmoscopy
- Clinical pathology
- P450 enzymes
- Gross lesions and organ weights
- Bone marrow d
- Incidence and images of spontaneous neoplastic and nonneoplastic changes
- Reproductive and developmental data
