Inbred rats

Brown Norway

BN/RijHsd

Brown, non-agouti. BN/RijHsd rats were derived from a nucleus colony obtained directly from the TNO Institute, the Netherlands.

Characteristics

Litter average: 4,5
Haplotype: RT1ⁿ
Hyper-responsive lungs
High incidence of bladder tumors in males

Research use

Allergic respiratory disease
Oncology
Aging
Leukemia
Nephrology

DA

DA/OlaHsd

Agouti. From A.R.C. Cambridge, United Kingdom; to Olac, United Kingdom, in 1979; to Harlan Laboratories, in 1992. Harlan became Envigo in 2015.

Characteristics

Litter average: 6,0
Haplotype: RT1^av1
Females have a defective bile acid transport

Research use

Experimental allergic encephalomyelitis
Induced rheumatoid arthritis
Oncology
Cardiovascular
Transplantation

Lewis

LEW/Han^®Hsd
LEW/SsNHsd

Albino. LEW/HanRHsd rats were descended from the Central Institute for Laboratory Animal Breeding (ZfV), Hannover, Germany. In 1994 to Harlan through acquisition.

LEW/SsNHsd rats were descended from a nucleus colony obtained from the National Institutes of Health, Bethesda, Maryland USA.
Han^® is a registered trademark of Envigo.

Charakteristika

Průměr vrhu: 7,5
Haplotype: RT1^l
Zvýšené hladiny sérového thyroxinu, inulinu a růstového hormonu
Dispozice k učení
Inbrední recipient pro několik kongenních kmenů
Vnímavý k navození autoimunních chorob

Characteristics

Litter average: 7,5
Haplotype: RT1^l
Inbred recipient for several congenic strains
Increased levels of serum thyroxine, insulin, and growth hormone
Susceptible to induction of autoimmune disease

Research use

Adjuvant-induced arthritis
Transplantation
Experimental allergic encephalomyelitis

Other available data

Clinical chemistry

Spontaneously Hypertensive

SHR/NHsd

Albino. Derived from a nucleus colony obtained from the National Institutes of Health, Bethesda, Maryland.

Characteristics

Litter average: 9,4
Haplotype: RT1^k

Research use

Model for Hypertension and Insulin Resistance

Other available data

To maintain the phenotype of SHR/NHsd rats, ENVIGO routinely screens future breeders utilizing the tail cuff method for acceptable blood pressure levels. On request we can monitor individual rats prior to shipment (at additional cost).

Wistar Kyoto

WKY/NHsd

Albino. Derived from a nucleus colony obtained from the National

Institutes of Health, Bethesda, Maryland

Characteristics

Litter average: 8,4
Haplotype: RT1^k
Normotensive control for SHR model

Additional strains of inbred rats

ACI/SegHsd
SR/JrHsd
SS/JrHsd
WF/NHsd

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